How we fund our mission

How we fund our mission

Funding for Alzheimer care, support, advocacy and research comes from individual donors and from organizations whose work is aligned with our mission. Our collaborative partners include government agencies, corporations, foundations and membership organizations.

With your helps we are able to accelerate our mission to eliminate Alzheimer's disease and to provide the best care and support to those living with Alzheimer's.

Mary Joseph Foundation a non-profit international organization for Alzheimer’s is interested in building relationships with companies to help increase awareness of Alzheimer's disease, our organization and generate funds to further our mission.

We are eager to work with you to explore how the Mary Joseph Foundation can best support your business goals and objectives. Some of the ways we can work together include cause-marketing programs, product royalty promotions and our expert professional IT services.

As President of Mary Joseph Foundation, I help CIO's and their senior teams translate complex issues into clear messages to speed organizational buy in and delivery of results. Whether introducing a new technology or complex security designs, delivering a new capability or rolling out a whole new strategy, meaningful communication is central to IT executives' ability to effect change. Few IT security consultants are able to communicate effectively in depth, government and corporation security technology insight that Mary Joseph Foundation provides, and few technology consultants can match our communication skill, knowledge and strengths. We are uniquely positioned to provide this essential service to IT executives here in America and around the world.

In addition, Mary Joseph Foundation work with IT leaders and provide governments and corporations with effective and communications services including consulting, training, seminars, designing, security policy, presentation on new products, online strategy development and group facilitation. We work with organizations to develop online and face-to-face communities and implement a new program write and speak effectively about the use of security technology and the danger of intruders who want to harm governments and other organizations. Large scale layer 3 Backbone Dual Paths for fast network recovery

As a longtime proponent and facilitator of peer-to-peer executive learning and knowledge sharing, I personally was involved in many IT projects to name a few, Cantor Fitzgerald, Morgan Stanley, Goldman Sachs, Prudential Financial, Colson Financial, Ernst & Young, Bass Brothers, Bank One and more. Mary Joseph Foundation is here to help in many ways.

Disaster recovery is a must

A wide variety of emergencies, like hurricanes, earthquakes, blizzards and other unforeseen disasters, require continuity planning throughout federal, state, local governments and big financial corporations. These disasters can have a widespread impact on an organization or agency and its ability to function and support the public due to the "immediate" loss of physical facility assets, application servers, network infrastructures, and more.

The Solution

A remote access plan is a critical component of an overall business continuity disaster recovery plan. Remote or isolated emergency workers must continue their critical roles during times of emergency, and must have secure and reliable access to an organization's key information databases and application servers.

Mary Joseph Foundation a non-profit international organization.

register with the Federal government and incorporated in the state of New Jersey

www.maryjosephfoundation.blogspot.com

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Frank Joseph ccda. ccnp. ccie.

President and CIO

Award winning former senior network and security Engineer Cisco. Citi Bank. JP MorganChase. IBM. and the US Federal Government.

Who was Mary Joseph ?

Who was Mary Joseph ?

Mary Joseph was born on August 11-1925, she was a very kind, loving and hard working lady, all her life she gave to other so much of her time especially with sick people, she also gave freely to those who did not had food, clothes, shoes, medicines and more.

Mary did this for over fifty years of her life, helping people especially in the third world countries she would used her own personal money each week to buy foods, medicine, shoes, clothes and more, she would shop in Newark, Jersey City, Elizabeth, New Jersey and New York. Then every week end she would pack the boxes and send them off with a smiling face.

Mary had a joy on her face especially when she was packing the boxes to send to these people who did not had anything to eat and were sick.

Mary always believe God love a cheerful giver so she gave willingly to others.

In the late 1980 Mary saw her two cousins Willie and Fann came down with Alzheimer's and it really devastated her, then in early 1991 Mary came down with Alzheimer's until 1998 she die from the Alzheimer's disease.

In Alzheimer’s disease many studies show memory for old events are preserved till the advanced stages of the disease. In the early stages, the ability to learn new things are impaired. Since the common man assumes that memory for old events are more important, some individuals who have Alzheimer's disease is not brought to the doctor who specialize in treating Alzheimer's disease in the early stages of the disease.

Even if a individual with changes in intellectual capability is taken to a doctor, general physicians with limited experience in treating Alzheimer’s disease will rarely make a specific diagnosis of this disease. Although awareness is increasing, many misconceptions prevail among medical practitioners. Some family members continue to make this mistake.

Mary Joseph Foundation a non-profit international organization.
register with the Federal government and incorporated in the state of New Jersey
137 1/2 Washington Ave, Suite 292
Belleville, New Jersey 07109

New Report Says over 10 Million Americans Will soon Develop Alzheimer's disease

New Report Says over 10 Million Americans Will soon Develop Alzheimer's disease

Every 22 seconds in the world and every 71 seconds in this country, someone is diagnosed with Alzheimer's disease, and a startling new report out today from the Alzheimer's Association predicts that one out of every eight baby boomers — or over 10 million Americans — is expected to develop the disease sometime in the near future. If new treatments are years away, is there anything you can do today that might prevent it?

Fran Hershkowitz's mother began losing her memory more than a decade ago, and now Fran, who is 63, worries if he might be next.

"It's frightening, too, to think that one day this is going to be me." the younger Hershkowitz said. Evidence shows that physical exercise may be the most effective remedy today to prevent Alzheimer's disease, and large health studies have shown that people who stay physically active are less likely to develop the disease. Scientists put that idea to the test. Researchers bred mice to develop the specific kind of plaque in the brain, as seen in Alzheimer's disease. Some mice were allowed to exercise, and some were not. The autopsy results were stunning.

The brains of sedentary mice were riddled with the harmful plaques, but the physically active mice had 50 to 80 percent less plaque. Further tests revealed that the mice who exercised produced twice as much of an enzyme in the brain that prevents plaque buildup. The exercise also produced twice as many tiny blood vessels in the brain to allow plaques to escape. "Moving plaques from the brain into the blood, so it's carried to those organs like the liver where it can be destroyed," said Professor Sangram S. Sisodia, a neuroscientist at the University of Chicago and lead investigator in the study. Population studies suggest any exercise that raises your heart rate for 30 to 45 minutes at least several times a week can lower your risk of Alzheimer's. And the more the exercise you get, the lower your risk. "Regular physical exercise is probably the best means we have of preventing Alzheimer's disease today," said Dr. Ronald Petersen, director of the Alzheimer's Research Center at the Mayo Clinic in Rochester, Minn.

"There are other possible intervention, including diet, and supplements, intellectual activities, but the data indicate that physical activity is the most likely to prevent this disease," Doctor William Thomas said. For family members determined to avoid another generation of this disease, there is finally preventative action they can take, which they won't have to wait for.

"Regular physical exercise is probably the best means we have of preventing Alzheimer's disease today." Dr. Ronald Petersen of the Mayo Clinic Alzheimer's Disease Research Center said. "Better than medications, better than intellectual activity, better than supplements and diet."

For family members determined to avoid another generation of this disease, there is finally preventative action they can take, which they won't have to wait for.

Mary Joseph Foundation a non-profit international organization for Alzheimer's disease.
137 1/2 Washington Ave, Suite 292, Belleville, NJ 07109.

Register and incorporated in the state of New Jersey.

www.maryjosephfoundation.blogspot.com

www.marycharityfoundation.blogspot.com
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Alois Alzheimer

Alois Alzheimer

Alois Alzheimer was born in 1864 in Markbreit in Bavaria, Southern Germany. Excelling in sciences at school he studied medicine in Berlin, Aschaffenburg Tubingen and Wurzburg where he graduated with a medical degree in 1887. He began work in the state asylum in Frankfurt am Main, becoming interested in research on the cortex of the human brain. Here he commenced his education in psychiatry and neuropathology.

Along with Franz Nissl, a colleague at the asylum, Alzheimer spent the following years working on a major six volume study, the 'Histologic and Histopathologic Studies of the Cerebral Cortex,' describing the pathology of the nervous system. The work was finally published between 1907 and 1918. In 1895 Alzheimer was appointed director of the asylum where he continued his research on a number of subjects including manic depression and schizophrenia.

Today, the pathological diagnosis of Alzheimer's disease is still generally based on the same investigative methods used in 1906. This is remarkable compared with the development of investigative methods for other diseases, and it speaks volumes about the quality of Alzheimer's discovery.

Alzheimer's disease is the most common cause of dementia and accounts for 65% - 80% of all cases. It destroys brain cells and nerves disrupting the transmitters which carry messages in the brain, particularly those responsible for storing memories. Alzheimer's disease was first described by A. Alzheimer's in 1906.

During the course of Alzheimer's disease, nerve cells die in particular regions of the brain. The brain shrinks as gaps develop in the temporal lobe and hippocampus, which are responsible for storing and retrieving new information. This in turn affects people's ability to remember, speak, think and make decisions. The production of certain chemicals in the brain, such as acetylcholine is also affected. It is not known what causes nerve cells to die but there are characteristic appearances of the brain after death. In particular, 'tangles' and 'plaques' made from protein fragments are observed under the microscope in damaged areas of brain. This confirms the diagnosis of Alzheimer's disease.

Currently there are over 30 million peoples worldwide who are living with Alzheimer’s disease and that number is expected to grow to well over 61 million by 2020. Alzheimer’s disease is the seventh leading cause of death in the United States and number six worldwide.

Mary Joseph Foundation a non-profit international organization for Alzheimer's disease.

register and incorporated in the state of New Jersey.

Mary Joseph Foundation
137 1/2 Washington Ave.Suite 292
Belleville, New Jersey 07109

Alzheimer's and the cells

Alzheimer's this disease form a widely dispersed areas of the brain, the senses send information to the hippocampal complex. here, where the information is packaged into memories, also is where Alzheimer's begins. The two hallmarks of the disease are amyloid beta plaques and tau tangles.

Amyloid beta plaque: One of the two anatomical hallmarks of Alzheimer's. Amyloid beta is a fragment derived from a larger protein called app, for amyloid precursor protein. In a healthy brain, these fragments are broken down and eliminated. In aging and diseased brains they accumulate between neurons, eventually causing their death.

Entorhinal cortex: Part of the hippocampal memory complex, the entorhinal cortex is the initial processing center for the informational bits of experience that are assembled into a memory.

Hippocampus:The central memory system, located in the medial temporal lobe. Memories are encoded here before being shipped out for storage to other locations in the neocortex.

Microtubules: Tunnel-like structures inside cells that help transport nutrients and other important biochemicals from one part of the neuron to another.

Neurofibrillary tangles: One of the two anatomical hallmarks of Alzheimer's. The other is amyloid beta plaque. In healthy cells, long tau protein fibers help maintain cells structure.

How nerve cells communicate

In Alzheimer's these paired helical filaments become tangled and destroy microtubules, thereby disrupting communication between neurons.

Tau: A protein present in all nerve cells, tau ...rhymes with now acts as a stabilizer of the microtubules.In Alzheimer's, an overproduction of tau causes tangles to develop and nerve cells to die.

Mary Joseph Foundation a non-profit international Organization for Alzheimer's

register and incorporated in the state of New Jersey

137 1/2 Washington Ave, Suite 292

Belleville, New Jersey 07109

Who get's Alzheimer's and at what age.

Alzheimer's disease is a progressive condition that damages areas of the brain involved in memory, intelligence, judgment, language, and behavior. It is the most common form of mental decline, or dementia, in adults age around 40s, 50s 60s 70s, 80s and in some rear cases in individuals in their thirties.

Alzheimer's disease always gets worse over time, but the course of the disease varies from person to person. While some people lose the ability to do daily activities very early on, others may still be able to function relatively for little while longer.

Physicians are sometimes reluctant to discuss in much detail what the future holds for someone with Alzheimer's disease. Their reticence is understandable. It's impossible to predict exactly how the disease will affect an individual because the symptoms and rate of progression vary. Some people develop severe psychiatric problems; others do not. A symptom can show up early or not appear until much later.

For some people, the decline is slow and gradual or longer; others experience a rapidly downhill course that ends in death within three to five years. The symptoms are also influenced by the person's intellectual abilities before the illness sets in, and by other health problems, personality, coping skills, and family or other support.

Over time, Alzheimer's disease causes severe mental and functional problems and eventually results in death. There is no cure for Alzheimer's disease. However, much can be done, including medicines and behavioral modifications, to maintain the person's quality of life and to help the person stay active. Many people with Alzheimer's disease can be cared for, to find out more you can send us an email or call us.

Mary Joseph Foundation a non-profit international organization for Alzheimer's disease.

Register and incorporated in the state of New Jersey.

www.maryjosephfoundation.blogspot.com

www.marycharityfoundation.blogspot.com
http://www.ammado.com/nonprofit/maryjosephfoundation/articles/all

Mary gave to everyone

First, she did loved everyone and gave to everyone with a smile on her face, herself, time, money and foods. She grew up poor and knew how it feel to be hungry and sick but what hurt her most at that time is when she saw so many others suffering from this slow and deadly disease, at that time Mary did not fully understood what is Alzheimer's, but she had always believe nothing is impossible and nothing name can't and she knew deep down in her heart there will be a cure for this slow and deadly disease name Alzheimer's sometime in the future, but in the mean time Mary was focusing on helping peoples who were sick, hungry, homeless and suffering.

She did always put herself in other people place and reminded everyone " to do unto others what you would like them do unto you" she did strongly believe no one should be hungry, sick and homeless. In all Mary did more for others than herself.

Mary Joseph Foundation a non-profit international organization for Alzheimer's disease.

Mary Joseph Foundation
137 1/2 Washington Ave, Suite 292
Belleville, NJ 07109