Mary Joseph foundation Charity for Alzheimer's Disease.

2010-08-09T12:17:00.001-07:00

Who was Mary Joseph ?

Mary Joseph was born on August 11-1925, she was a very kind, loving and hard working lady, all her life she gave to other so much of her time especially with sick people, she also gave freely to those who did not had food, clothes, shoes, medicines and more.

Mary did this for over fifty years of her life, helping people especially in the third world countries she would used her own personal money each week to buy foods, medicine, shoes, clothes and more, she would shop in Newark, Jersey City, Elizabeth, New Jersey and New York. Then every week end she would pack the boxes and send them off with a smiling face.

Mary had a joy on her face especially when she was packing the boxes to send to these people who did not had anything to eat and were sick.

Mary always believe God love a cheerful giver so she gave willingly to others.

In the late 1980 Mary saw her two cousins Willie and Fann came down with Alzheimer's and it really devastated her, then in early 1991 Mary came down with Alzheimer's until 1998 she die from the Alzheimer's disease.

In Alzheimer’s disease many studies show memory for old events are preserved till the advanced stages of the disease. In the early stages, the ability to learn new things are impaired. Since the common man assumes that memory for old events are more important, some individuals who have Alzheimer's disease is not brought to the doctor who specialize in treating Alzheimer's disease in the early stages of the disease.

Even if a individual with changes in intellectual capability is taken to a doctor, general physicians with limited experience in treating Alzheimer’s disease will rarely make a specific diagnosis of this disease. Although awareness is increasing, many misconceptions prevail among medical practitioners. Some family members continue to make this mistake.

Mary Joseph Foundation a non-profit international organization.
register with the Federal government and incorporated in the state of New Jersey
137 1/2 Washington Ave,
Belleville, New Jersey 07109

2010-08-09T12:14:00.000-07:00

Some famous people who died from Alzheimer’s disease

In Alzheimer’s disease, memory for old events are preserved till the advanced stages of the disease. In the early stages, the ability to learn new things are impaired. Since the common man assumes that memory for old events are more important, some individuals who have Alzheimer's disease is not brought to the doctor in the early stages of the disease.

Some famous people who died from Alzheimer’s disease

Adcock, Joe
baseball player

Astor Brooke

was an American philanthropist and socialite

Albertson, Mabel
actress

Andrews, Dana
actor

Balanchine, George
dancer, choreographer

Bing, Rudolph
opera impresario

Brooks, James
artist

Burrows, Abe
author

Chen, Joyce
chef

Copeland, Aaron
composer

DeKooning, Willem
artist

Dorsey, Thomas, A
father of gospel music

Fears, Tom
hall of fame professional football player and coach

Feraud, Louis
prominent fashion designer

Francis, Arlene
actress

Frankovich, Mike
movie producer

French, John Douglas
physician

Estelle Getty

actress

Goldwater, Barry
Arizona Senator

Heston Charlton

actor

Hayworth, Rita
actress

Henriquez, Raul Silva
Roman Catholic cardinal, human rights advocate

Joseph Mary

Mary Joseph Foundation

Klutznick, Philip
real estate developer, adviser to five U.S. Presidents

Leroy, Mervyn
director - 1987

Lord, Jack
actor

MacDonald, Ross
author

Meredith, Burgess
actor

Murdoch, Iris
author

O’Brien, Edmond
actor

O’Connell, Arthur
actor

Owen, Marv
baseball player

Picon, Molly
actress

Preminger, Otto
director

Quackenbush, Bill
hall of fame professional hockey player

Reagan, Ronald
former President of USA

Ritz, Harry
performer

Robinson, Sugar Ray
boxer

Rockwell, Norman
artist

Scott, Simon
actor

Shulman, Irving
screenwriter

Schwartz, Betty
first woman to win an Olympic gold medal in track events

Swift, Kay
composer

Van Vogt, Alfred
science fiction writer

White, E.B.
author

Wilson, Harold
British Prime Minister

Mary Joseph Foundation a non-profit international organization

Charlton Heston 1924-2008

Mary Joseph Foundation extends its deepest sympathies to the Heston family on the passing of Charlton Heston on Saturday, April 5. In 2002, Mr. Heston courageously announced to the public that he was suffering with symptoms consistent with Alzheimer’s disease.

Currently there are over 8 million Americans living with dementia/Alzheimer’s disease and that number is expected to grow to as many as 30 to 35 million by 2050. Alzheimer’s disease is the seventh leading cause of death in the United States and growing.

Researchers are close to developing accurate ways to diagnose and treat Alzheimer’s, but current Alzheimer's funding is nowhere near enough. Significantly increased federal funding for Alzheimer's research, education and care is imperative to reach the goal of a world without Alzheimer’s.

Estelle Getty Born: July 25, 1924 in New York City, New York Occupation: Actor: ... She played Sophia on Golden Girls from 1985 to 1992...We at the Mary Joseph Foundation are sorry to hear about Estelle Getty condition, for sometime now she had developed and been living with dementia and later coming down with Alzheimer's.

Brooke Astor (March 30, 1902 – August 13, 2007) was an American philanthropist and socialite who was the chairwoman of the Vincent Astor Foundation, in 2000 Brooke Astor was diagnosis by her doctor of having Alzheimer's disease...On August 13, 2007 she died from Alzheimer's.

Although there is no cure as yet for Alzheimer’s disease, a lot can be done to make the individuals with Alzheimer's disease more comfortable.

Learn more about Alzheimer:

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Mary Joseph Foundation a non-profit organization for Alzheimer's disease.
137 1/2 Washington Ave,
Belleville, NJ 07109

2010-08-09T12:11:00.000-07:00

Long-term care for Alzheimer's

There may come a time when it is too difficult for you to care for your loved one at home. As the disease progresses, your job will become increasingly difficult — despite a variety of community services — to the point where long-term residential care may be the most responsible option.

Making the decision

As you come to terms with residential care, you may grapple with feelings of guilt that you're abandoning the person. You may assume incorrectly that people who wind up in nursing homes were discarded by their families. But the truth is just the opposite. Most families exhaust every other option before resorting to this type of arrangement, and, contrary to popular belief, most families do stay connected to the individual and visit often. You can also draw comfort in knowing that there are an increasing number of good programs that specialize in care and treatment of people with Alzheimer's disease.

Better understanding for Alzheimer's patient care

There has been a shift in the general philosophy of caring for people with dementia. In the past, the general consensus was that they should be continually oriented to reality. For instance, if a person talked about visiting a sister who had died, the caregiver would remind the person what year it was and that the relative wasn't alive. Experts recommended responses like "No, I'm not your daughter, I'm your nurse."

Experts now believe that these efforts are futile and only frustrate the individual. Today, the preferred approach is to validate the person's feelings. For instance, responses like "You must really love her" to a man who talks about his dead wife, rather than, "She died 8 years ago," fosters emotional well-being. Repeated validation may also curb some behavior problems associated with frustration.

Resurrecting the patients remove frustration

There is also more of an attempt to resurrect what's left of the person's "self." In high-quality programs, caregivers try to understand each person's past interests and plan activities accordingly. If, for example, a person loved to dance, he or she may still derive considerable enjoyment from music and dance activities at a center.

In one case involving someone who had been a newspaper reporter most of his life, his caregivers set up a makeshift newsroom with a typewriter and assigned him the task of writing a newsletter for the center. He was able to enjoy this until typing became too frustrating. Although his caregivers eventually removed the typewriter, they still reinforced the idea that he was working in a newsroom. In another case, a caregiver arranged for several former stamp collectors in the assisted-living facility to see a stamp exhibit that was in town. Despite their disease, the caregiver said they seemed to thoroughly enjoy the experience.

Real facts

Over half of all individuals living in nursing homes have Alzheimer's disease or another dementia.

Evaluating a home for Alzheimer's patient

Keep in mind that not all specialized Alzheimer's care is equal. When you visit a home, try to determine what makes it unique.For up to date information on the wide variety of options available and how to evaluate them because the Alzheimer's patient may live for as long as 4 to 8 years and during that time the patient will gets worse in a regressive state, contact the Mary Joseph Foundation.

Please remember these

When you visit a facility, ask plenty of questions, such as these:

How is the program geared specifically for people with Alzheimer's disease?
Are the caregivers trained in the treatment of Alzheimer's?
Is it a homelike environment?
Are residents engaged in meaningful activities?
Does the facility incorporates design features that can be helpful to those with Alzheimer's, such as enhanced lighting, color-coded hallways, and plenty of walking room?
Is the environment safe? How secure is it for people who wander?
How would an upset resident be handled?
How many people live there? What's the ratio of staff members to residents?
Can medical care be given on site if needed? Who provides it? Skilled nurses? Visiting physicians?
What personal items can the resident bring?
Are skilled professionals — including registered nurses, licensed practical nurses, and certified nursing assistants — on duty at all times?
How long and often may family members visit?
What's the cost? Does the facility requires you to pay privately?
If the patient needs to change to Medicaid funding after a few years, will he or she be able to remain at the facility?
Under what circumstances would a resident be required to leave?

Remember the average cost today of long-term care is between $39,860 a year for an assisted-living facility and $82,095 a year for a private room in a nursing home, you'll have to investigate payment options.

Remember we are here to help.

http://www.maryjosephfoundation.blogspot.com/

www.marycharityfoundation.blogspot.com

2010-08-09T12:10:00.000-07:00

Progressive memory loss.

This is the hallmark of Alzheimer's disease. Initially, only short-term memory is impaired, and the person merely seems forgetful. But because short-term memory is essential for absorbing new information, the impairment soon interferes with the ability to interact socially and perform one's work. Long-term memory may be retained longer, often in great detail, but it becomes fragmented as the disease progresses. Toward the final stage, people with Alzheimer's may be unable to recall their own names.

The cerebral cortex

The third level of the brain is the cerebral cortex, commonly called the "gray matter." The cerebral hemispheres contain two specialized regions, one dedicated to voluntary movement and one to processing sensory information. But most of the gray matter is the association cortex, which becomes progressively larger as animals move up the evolutionary ladder. The association cortex is the region of conscious thought: It is where you store memory and language skills, process information, and carry out creative thinking.

Inside the brain

In Alzheimer's disease, brain cells die and neuronal connections wither in all parts of the brain, but especially in the hippocampus and the amygdala — important parts of the limbic system that coordinate memory storage and recall — and the cerebral cortex, the seat of higher-level thinking, memory, and language.

A micro view of the brain

Up close, the brain is a web of interconnecting cells called neurons. How these cells communicate and what happens when these cells die form the basis of our understanding of brain disease.

How brain cells communicate

The neuron is the brain's basic unit for processing information. The human brain contains an incredible number of neurons — about 100 billion, give or take 10 billion. The neuron is a unique cell in activity and appearance. It generates both electrical and chemical signals, making it able to communicate quickly with distant neurons. Instead of the compact shape typical of other cells in the body, the neuron is like an oak tree with giant branches stretched out. Each neuron has a body containing a nucleus, one long fiber called an axon, and many shorter branching fibers called dendrites.

The neuron is both a receiver and a transmitter. When a neuron receives a signal, it generates an electrical impulse. This impulse travels through the neuron and down the axon to its end (the axon terminal). The signal is then passed on to other neurons. Viewed under a microscope, neurons look like a dense forest of trees whose branches are so closely intertwined that they appear to touch. But when the details are highlighted with a silver stain, it is clear that each cell is separated from its neighbors by tiny gaps called synapses. Because the electrical signal cannot bridge this space, some other mechanism is required for a neuron to communicate with its neighbors. This is where the neuron's chemical signal comes in.

Stored in the axon terminal are chemical messengers called neurotransmitters. The electrical impulse opens tiny pores in the axon terminal, allowing a supply of neurotransmitters to flood into the synapse. The chemical then attaches to receptors on a neighboring neuron. What happens next depends on whether the neurotransmitter has an exciting or inhibiting effect on the neuron.

How nerve cells communicate

Electrical signal travels down axon of neuron.
Chemical neurotransmitter is released.
Neurotransmitter binds to receptor site.
Signal continues into new neuron.
Reuptake occurs; neurotransmitter is transported back into the cell that released it.

An excitatory neurotransmitter passes the message on by creating an electrical impulse in the cell that receives it, and the process of electrical-to-chemical signaling is repeated. But if an impulse were to be transmitted to every neuron in the brain, the result would be chaos; much like a power surge can cause a short circuit, neurons firing all at once would cause a prolonged epileptic seizure. To safeguard against this happening, inhibitory neurotransmitters suppress communication to neighboring neurons.

Of the more than 20 chemical messengers discovered thus far, a few are fairly well understood. Several of them are involved in memory, including acetylcholine, serotonin, and dopamine. Many of these neurotransmitters have additional functions; for example, serotonin helps regulate sleep and sensory perception, while dopamine helps regulate movement.

As biological processes go, the speed of thought is rapid (although slow compared with a computer). Electrical impulses in some neurons reach speeds of nearly 200 mph, and transmission from cell to cell takes about a thousandth of a second. In addition, one nerve cell may have more than 1,000 synapses and, with a single impulse, can transmit simultaneously to all its neighbors.

Plaques and tangles

The brains of Alzheimer's patients contain neurofibrillary tangles inside neurons and clumps of fibers called neuritic plaques outside of neurons. A set of enzymes, called secretases, in the neurons cause plaques to form. The secretases snip pieces from a large amyloid precursor protein (APP), leaving behind fragments of amyloid proteins that snarl and clump with the debris of dying neurons (pieces of dendrites). In contrast to the neuritic plaques, neurofibrillary tangles form within neurons and are composed of aggregates of a different protein known as tau.

Beta-amyloid is a peptide composed of approximately 40 amino acids. Research has shed light on the chemical process responsible for the formation and deposit of this sticky, starchlike protein in the brains of Alzheimer's patients. This understanding has prompted pharmaceutical companies to start manufacturing drugs to block the formation of amyloid deposits (see "Amyloid production blockers").

These tangles and plaques, first described by Alois Alzheimer in 1907, have been the main focus of research for decades, and for good reason: The worse the mental deterioration, the more amyloid and tangles are found in brain tissue. The prevailing view among neurologists used to be that these deposits caused the mental changes in Alzheimer's disease.

However, tangles and plaques are not unique to this condition. Some are found in other dementing disorders, and a few are scattered about in the brains of healthy middle-aged and elderly people. Some neuroscientists have wondered if these occasional deposits might explain the mild forgetfulness associated with normal aging, but studies have cast doubt on this theory.

Studies now indicate that dementia in Alzheimer's patients is caused by the shrinkage and death of neurons and synaptic loss, not by tangles and plaques themselves. However, according to the leading hypothesis, amyloid deposits play an early role by setting in motion a cascade of biochemical events that causes the cells to shrink and die.

With advances in technology enabling them to count neurons, neuroscientists were able to make this discovery by examining brain tissue from 10 people with normal brain function who died after age 60. All the samples contained about the same number of neurons in an area of the association cortex richly supplied with nerves from the sensory region. For the first time, scientists had a standard for defining how many neurons were "normal" in the human brain. Furthermore, this finding indicated that neuron loss was not a product of normal aging.

Next, the researchers compared the normal samples with brain tissue from 10 people with Alzheimer's and discovered, on average, a 41% reduction in the number of neurons. And the longer dementia had been present, the fewer neurons were found. There was also a correlation with neurofibrillary tangles: People with the greatest neuron loss had more tangles, about 95% of which were inside the remaining neurons. However, loss of neurons was dramatically greater than the number of tangles.

The researchers offered "housekeeping" as a possible explanation for this discrepancy: Molecules that clear away dead cells in the body eventually removed the tangles. When they counted neuritic plaques, the researchers found no relationship with either neuron loss or disease duration, reinforcing the view that neuronal dysfunction and death cause dementia. Although tangles and plaques are still considered the diagnostic hallmarks of Alzheimer's disease, synaptic loss and neuron death correlate best with dementia.

Experts also believe that decreased levels of the neurotransmitter acetylcholine, a chemical that bridges synapses between neurons that affect memory, also contribute to the memory loss of Alzheimer's disease. In the cortex and hippocampus, where this neurotransmitter is needed for memory and learning, the acetylcholine-producing neurons (called cholinergic neurons) are normally plentiful. But of the several types of neurons that can degenerate in Alzheimer's disease, the cholinergic neurons are especially hard hit. As acetylcholine production falls in the cortex and hippocampus, dementia becomes progressively worse. By the time someone with Alzheimer's disease dies, the cortex may have lost 90% of its acetylcholine.

Other neurotransmitter abnormalities may also be present. Reduced levels of serotonin and noradrenaline have been found in some people with Alzheimer's disease. Imbalances among these and other neurotransmitters could explain why some patients experience sensory disturbances, depression, sleep problems, aggressive behavior, and mood swings.

Mary Joseph Foundation

137 1/2 Washington Ave,

Belleville, New Jersey 07109

2009-12-22T07:54:00.000-08:00

Who get's Alzheimer's and at what age.

Alzheimer's disease is a progressive condition that damages areas of the brain involved in memory, intelligence, judgment, language, and behavior. It is the most common form of mental decline, or dementia, in adults age around 40s, 50s 60s 70s, 80s and in some rear cases in individuals in their thirties.

Alzheimer's disease always gets worse over time, but the course of the disease varies from person to person. While some people lose the ability to do daily activities very early on, others may still be able to function relatively for little while longer.

Physicians are sometimes reluctant to discuss in much detail what the future holds for someone with Alzheimer's disease. Their reticence is understandable. It's impossible to predict exactly how the disease will affect an individual because the symptoms and rate of progression vary. Some people develop severe psychiatric problems; others do not. A symptom can show up early or not appear until much later.

For some people, the decline is slow and gradual or longer; others experience a rapidly downhill course that ends in death within three to five years. The symptoms are also influenced by the person's intellectual abilities before the illness sets in, and by other health problems, personality, coping skills, and family or other support.

Over time, Alzheimer's disease causes severe mental and functional problems and eventually results in death. There is no cure for Alzheimer's disease. However, much can be done, including medicines and behavioral modifications, to maintain the person's quality of life and to help the person stay active. Many people with Alzheimer's disease can be cared for, to find out more you can send us an email or call us.

Mary Joseph Foundation a non-profit international organization for Alzheimer's disease.

http://www.maryjosephfoundation.blogspot.com/

2009-10-15T06:47:00.000-07:00

New Report Says over 10 Million Americans Will soon Develop Alzheimer's disease

Every 22 seconds in the world and every 71 seconds in this country, someone is diagnosed with Alzheimer's disease, and a startling new report out today from the Alzheimer's Association predicts that one out of every eight baby boomers — or over 10 million Americans — is expected to develop the disease sometime in the near future. If new treatments are years away, is there anything you can do today that might prevent it?

Fran Hershkowitz's mother began losing her memory more than a decade ago, and now Fran, who is 63, worries if he might be next.

"It's frightening, too, to think that one day this is going to be me." the younger Hershkowitz said. Evidence shows that physical exercise may be the most effective remedy today to prevent Alzheimer's disease, and large health studies have shown that people who stay physically active are less likely to develop the disease. Scientists put that idea to the test. Researchers bred mice to develop the specific kind of plaque in the brain, as seen in Alzheimer's disease. Some mice were allowed to exercise, and some were not. The autopsy results were stunning.

The brains of sedentary mice were riddled with the harmful plaques, but the physically active mice had 50 to 80 percent less plaque. Further tests revealed that the mice who exercised produced twice as much of an enzyme in the brain that prevents plaque buildup. The exercise also produced twice as many tiny blood vessels in the brain to allow plaques to escape. "Moving plaques from the brain into the blood, so it's carried to those organs like the liver where it can be destroyed," said Professor Sangram S. Sisodia, a neuroscientist at the University of Chicago and lead investigator in the study. Population studies suggest any exercise that raises your heart rate for 30 to 45 minutes at least several times a week can lower your risk of Alzheimer's. And the more the exercise you get, the lower your risk. "Regular physical exercise is probably the best means we have of preventing Alzheimer's disease today," said Dr. Ronald Petersen, director of the Alzheimer's Research Center at the Mayo Clinic in Rochester, Minn.

"There are other possible intervention, including diet, and supplements, intellectual activities, but the data indicate that physical activity is the most likely to prevent this disease," Doctor William Thomas said. For family members determined to avoid another generation of this disease, there is finally preventative action they can take, which they won't have to wait for.

"Regular physical exercise is probably the best means we have of preventing Alzheimer's disease today." Dr. Ronald Petersen of the Mayo Clinic Alzheimer's Disease Research Center said. "Better than medications, better than intellectual activity, better than supplements and diet."

For family members determined to avoid another generation of this disease, there is finally preventative action they can take, which they won't have to wait for.

Mary Joseph Foundation a non-profit international organization for Alzheimer's disease.

http://www.maryjosephfoundation.blogspot.com/

www.marycharityfoundation.blogspot.com

2009-10-02T11:31:00.000-07:00

Alois Alzheimer

Alois Alzheimer was born in 1864 in Markbreit in Bavaria, Southern Germany. Excelling in sciences at school he studied medicine in Berlin, Aschaffenburg Tubingen and Wurzburg where he graduated with a medical degree in 1887. He began work in the state asylum in Frankfurt am Main, becoming interested in research on the cortex of the human brain. Here he commenced his education in psychiatry and neuropathology.

Along with Franz Nissl, a colleague at the asylum, Alzheimer spent the following years working on a major six volume study, the 'Histologic and Histopathologic Studies of the Cerebral Cortex,' describing the pathology of the nervous system. The work was finally published between 1907 and 1918. In 1895 Alzheimer was appointed director of the asylum where he continued his research on a number of subjects including manic depression and schizophrenia.

Today, the pathological diagnosis of Alzheimer's disease is still generally based on the same investigative methods used in 1906. This is remarkable compared with the development of investigative methods for other diseases, and it speaks volumes about the quality of Alzheimer's discovery.

Alzheimer's disease is the most common cause of dementia and accounts for 65% - 80% of all cases. It destroys brain cells and nerves disrupting the transmitters which carry messages in the brain, particularly those responsible for storing memories. Alzheimer's disease was first described by A. Alzheimer's in 1906.

During the course of Alzheimer's disease, nerve cells die in particular regions of the brain. The brain shrinks as gaps develop in the temporal lobe and hippocampus, which are responsible for storing and retrieving new information. This in turn affects people's ability to remember, speak, think and make decisions. The production of certain chemicals in the brain, such as acetylcholine is also affected. It is not known what causes nerve cells to die but there are characteristic appearances of the brain after death. In particular, 'tangles' and 'plaques' made from protein fragments are observed under the microscope in damaged areas of brain. This confirms the diagnosis of Alzheimer's disease.

Currently there are over 30 million peoples worldwide who are living with Alzheimer’s disease and that number is expected to grow to well over 61 million by 2020. Alzheimer’s disease is the seventh leading cause of death in the United States and number six worldwide.

Mary Joseph Foundation a non-profit international organization for Alzheimer's disease.

Mary Joseph Foundation
137 1/2 Washington Ave.
Belleville, New Jersey 07109

2009-10-02T08:09:00.001-07:00

Alzheimer's and the cells

Alzheimer's this disease form a widely dispersed areas of the brain, the senses send information to the hippocampal complex. here, where the information is packaged into memories, also is where Alzheimer's begins. The two hallmarks of the disease are amyloid beta plaques and tau tangles.

Amyloid beta plaque: One of the two anatomical hallmarks of Alzheimer's. Amyloid beta is a fragment derived from a larger protein called app, for amyloid precursor protein. In a healthy brain, these fragments are broken down and eliminated. In aging and diseased brains they accumulate between neurons, eventually causing their death.

Entorhinal cortex: Part of the hippocampal memory complex, the entorhinal cortex is the initial processing center for the informational bits of experience that are assembled into a memory.

Hippocampus:The central memory system, located in the medial temporal lobe. Memories are encoded here before being shipped out for storage to other locations in the neocortex.

Microtubules: Tunnel-like structures inside cells that help transport nutrients and other important biochemicals from one part of the neuron to another.

Neurofibrillary tangles: One of the two anatomical hallmarks of Alzheimer's. The other is amyloid beta plaque. In healthy cells, long tau protein fibers help maintain cells structure.

How nerve cells communicate

In Alzheimer's these paired helical filaments become tangled and destroy microtubules, thereby disrupting communication between neurons.

Tau: A protein present in all nerve cells, tau ...rhymes with now acts as a stabilizer of the microtubules.In Alzheimer's, an overproduction of tau causes tangles to develop and nerve cells to die.

Mary Joseph Foundation a non-profit international Organization for Alzheimer's

137 1/2 Washington Ave,

Belleville, New Jersey 07109

Mary gave to everyone

2009-09-21T10:45:00.000-07:00

First, she did loved everyone and gave to everyone with a smile on her face, herself, time, money and foods. She grew up poor and knew how it feel to be hungry and sick but what hurt her most at that time is when she saw so many others suffering from this slow and deadly disease, at that time Mary did not fully understood what is Alzheimer's, but she had always believe nothing is impossible and nothing name can't and she knew deep down in her heart there will be a cure for this slow and deadly disease name Alzheimer's sometime in the future, but in the mean time Mary was focusing on helping peoples who were sick, hungry, homeless and suffering.

She did always put herself in other people place and reminded everyone " to do unto others what you would like them do unto you" she did strongly believe no one should be hungry, sick and homeless. In all Mary did more for others than herself.

Mary Joseph Foundation a non-profit international organization for Alzheimer's disease.

Mary Joseph Foundation
137 1/2 Washington Ave,
Belleville, NJ 07109

Alzheimer's disease and the deadly effect

2009-09-21T10:34:00.000-07:00

Until the late 1970s, the study of such personal memory was not considered suitable for scientific inquiry. Whatever played across the mind's screen was private and unknowable to the outside world.This lack of knowledge about how memory works made it almost impossible to unravel one of medicine's most vexing questions - the cause of Alzheimer's, an age-related disease affecting more than eight million Americans.

But an examination of the latest research, some of it not yet published, shows that, neuron by neuron, scientists are finally making their way into the deepest recesses of human memory. Like the first blurry, black-and-white pictures sent back from the surface of the moon, the view is still imperfect, but memory's secret landscape is slowly being revealed.For example Scientific are now using laser and different type of wire devices to cause regression to the memory.

Science is unlocking many of the mysteries of the brain, but we don’t have all the answers yet. You can do everything “right” and still not prevent Alzheimer’s disease. What’s offered here is the best and most up-to-date information available so that you can make your own decisions about your health...There are still no cure for this disease.

Mary Joseph Foundation a non-profit international organization for Alzheimer's disease
137 1/2 Washington Ave,
Belleville, NJ 07109

Sugar. diabetics some Solution.

2009-09-18T08:27:00.000-07:00

Having control of blood sugar levels is never too easy, which is what makes The Sugar Solution even more intriguing. Bad sleeping habits, depression, sluggishness, inability to lose weight can all be attributed to an imbalance of blood sugar. The Sugar Solution fights all of these symptoms by putting the Glycemic Index to work in a person's favor.

Sleep provides more than a chance to dream. Scientists are waking up to the fact that the right amount of shut-eye restores bones, gives the brain a much-needed break from the daily grind, and prevents a whole host of maladies, including heart disease. In 2007, British researchers reported that snoozing five hours or less every night doubles a person's risk of developing a cardiovascular illness. Here are a few other reasons more quality sack time should be priority No. 1 for the 68 percent of Americans who get less than eight hours of sleep each night:

A lack of Z's can clog your arteries.

An article in a recent issue of the Journal of the American Medical Association claimed that study subjects who slept five hours or less were more likely than their better-rested peers to accumulate calcium deposits in their coronary arteries, a condition that can make the arteries less flexible and lead to heart disease. Researchers concluded that those who got less than the recommended eight hours every night could cut their calcification risk by a third and enjoy a blood-pressure drop as great as 16.5 points if they added just one hour of sleep to their nightly routine.

One group that knows all too well sugar's ravaging effects: people with diabetes, who—because they can suffer from years of undetected high blood sugar—often show early signs of skin aging. "Depending on how well their disease is controlled, diabetics can have up to 50 times the number of AGEs in their skin as those who don't have diabetes," says Karyn Grossman, MD, a dermatologist in New York City and Santa Monica, CA, and chief of the division of dermatology at St. John's Hospital in Santa Monica. It's never too late to turn back.

Cut back on the sweet stuff in your diet

It's not easy to eliminate sugar completely. Even whole grains, fruits, and vegetables turn to glucose— the type of sugar that fuels glycation—when digested. But limiting added sugar can help. Some guidelines:

Keep added sugar to no more than 10% of total calories

If you're a 40-year-old woman of average height (5-foot-5), that's 160 calories (or 10 teaspoons)from added sugar—about the number in one 12-ounce can of Coca-Cola or six Hershey's Kisses. By comparison, the average American consumes 31 teaspoons per day of added sugar, or the equivalent of 465 calories. (To find out how many calories total you should eat every day, log on to prevention.com/caloriecalculator.)

Watch for hidden sugar in food

Many prepared foods contain hefty amounts of sugar—but it's hidden under aliases—including barley malt, corn syrup, dextrose, fruit juice concentrate, maltose, maple syrup, molasses, and turbinado—on ingredient panels. The key is determining how many teaspoons of sugar each serving contains. Doing this is easy: Check the nutrition label for sugars, which are listed in grams under total carbohydrates, and then divide that number by 4 (each teaspoon of sugar is equal to 4 g) to convert it to teaspoons. For example, if sugars are listed as 12 g, you're getting 3 teaspoons of sugar per serving.

Avoid high fructose corn syrup

This type of sweetener, which is made by changing the sugar in cornstarch to fructose (another form of sugar), is believed to produce more AGEs than other types. Because HFCS extends the shelf life of foods and is sweeter and cheaper than other sugars, it's a popular ingredient in soda, fruit- flavored drinks, and packaged foods such as breads, crackers, and other snacks. You can spot it in ingredient lists on nutrition labels.

Supplement Your Diet

with at least 1 mg of vitamins B1 and B6 a day. These vitamins proved to be potent AGE inhibitors in a number of published studies, says David J. Goldberg, MD, a New York City–based dermatologist and a clinical professor of dermatology at Mount Sinai School of Medicine. B1 and B6 are plentiful in food, but taking a multivitamin—most of which deliver at least 1 mg of both Bs—ensures you're getting the daily value of 1.1 mg for B1 and 1.3 mg for B6 (1.5 mg after age 50).

Take A Crack At Good Nutrition

Recent research has uncovered some "eggs-traordinary" findings about eggs. The once frowned upon breakfast food is actually quite nutritious. In the past, eggs got a bad rap for being a cholesterol-rich food. However, the latest research suggests eating whole eggs may actually result in significant improvement in one's blood lipids. Eggs contain a wide array of essential vitamins and minerals and supply high-quality protein, carbohydrates and fat. A single egg provides approximately 5.5 grams of protein. In addition to their wonderful nutritional content, eggs have been shown to aid in weight loss.

Mary Joseph Foundation a non-profit international organization Alzheimer's.

http://www.maryjosephfoundation.blogspot.com/

www.marycharityfoundation.blogspot.com

Diet for healthy living.

2009-09-18T08:13:00.000-07:00

Just as some dietary fats can protect against cardiovascular disease and others can increase the risk, several studies suggest that the same is true for Alzheimer's disease. Diets that are high in damaging saturated fats and trans fats appear to increase the risk of Alzheimer's disease, whereas diets that are high in heart-healthy monounsaturated and polyunsaturated fats appear to decrease the risk. Saturated fats come mainly from meat and dairy, and trans fats from processed foods made with partially hydrogenated oils. Sources of healthy unsaturated fats include nuts, olive oil, canola oil, and fish such as SALMON and COD.

A 2004 study on Health and you, for example, followed 1000 cognitively normal people ages 50 and older for eight years. By the end of the study, the people who ate the most saturated and trans fats were twice as likely to have Alzheimer's disease as the people who consumed the least. However, the people who ate the most mono- and polyunsaturated fats were 76% less likely to develop Alzheimer's than the people who ate the least of these healthy fats.

Several other studies have found a benefit specifically from eating fish that is rich in omega-3 fatty acids, a type of polyunsaturated fat. Salmon, mackerel, and sardines are good sources. One 2007 study in health and you found that people who ate fatty fish more than twice a week had a 38% lower risk of dementia and a 46% lower risk specifically of Alzheimer's disease than people who ate fatty fish less than once a month. This study did not find a protective effect from eating lean fried fish.

Many unanswered questions about diet remain, however. It is unclear whether fish oil supplements are also beneficial. If fish does reduce the risk of various types of dementia, it could be because of its protective effect against cardiovascular disease. But fish may also benefit the brain directly. In a 2007 study reported in health and you on Aging, researchers found that a diet supplemented with omega-3 fatty acids limited the accumulation of beta-amyloid in the brains of mice bred to develop Alzheimer's disease. Whether people would enjoy the same benefit remains to be seen, but in the meantime, it can't hurt to replace the unhealthy fats in your diet with healthy ones.

Mary Joseph Foundation a non-profit international organization for Alzheimer's disease

Exercise 'slows down Alzheimer's and Singles 'face Alzheimer's risk'

2009-09-18T07:56:00.000-07:00

Exercise may ward off Alzheimer's and slow down its progression

Being physically fit could hold back the advance of Alzheimer's disease, US researchers have suggested.
Their study, published in the journal Neurology, looked at 121 people aged over 60, around half of them in the early stages of the disease.
Those with Alzheimer's who were less fit had four times more signs of brain shrinkage than those who were fit.

The Alzheimer's Research Trust said other research showed exercise reduced the risk of dementia.

People with early Alzheimer's disease may be able to preserve their brain function for a longer period of time by exercising regularly

Dr Jeffrey Burns
University of Kansas School of Medicine

Well over 700,000 people today in the UK are living with dementia, with this number predicted to grow quickly over the next two decades, as the proportion of older people in the population increases.

Other studies looking at the relationship between dementia and exercise tend to focus on whether being active can reduce the risk of the condition developing in the first place.

Dr Jeffrey Burns, from the University of Kansas School of Medicine, said his was one of the first to look at whether exercise could affect the progress of the illness.
His volunteers underwent a treadmill test to see how fit they were and then their brains were scanned for shrinkage, which is one way of measuring the severity of their Alzheimer's.

Enriched environment
Exercise offers an impressive array of health benefits. It helps prevent heart disease and type 2 diabetes; lowers the risk for high blood pressure, colon cancer, and breast cancer; and helps relieve insomnia, anxiety, and depression. But that's not all. Several studies suggest that exercise might also help ward off Alzheimer's disease and other forms of dementia.

One study of 2,000 people, published in 2005 in Lancet Neurology, found that those who exercised during midlife for 20 to 30 minutes twice a week were at least 50% less likely to develop Alzheimer's disease or another dementia in the following decades than people who were sedentary. Earlier, a Canadian study involving 9,000 people over age 60 found that regular exercise cut the risk for cognitive impairment by 37%. Studies of seniors in the United States and the Netherlands have yielded similar results.

Just how exercise may prevent Alzheimer's disease is unclear, but research on mice offers a clue. A 2005 study in the Journal of Neuroscience reported that mice that used their treadmills most often not only proved better able to learn how to get around test mazes than others, but also had fewer deposits of beta-amyloid in their brains. And in the environmental enrichment study described previously, the lowest levels of beta-amyloid and amyloid deposits were found in the most active mice, who spent the most time running and climbing on the toys placed in their cages.

Singles 'face Alzheimer's risk'

Social interaction may be key

Being single when you reach middle age could mean more than having the house to yourself - it could increase your risk of dementia.

Swedish research, presented at a US conference, found that marriage or having a partner halved the risk of developing dementia.

Scientists believe social interaction between couples may ward off illness.

The Alzheimer's Research Trust said the results were worrying, given the high divorce rates in the UK.

These findings are particularly worrying for the UK - a society with a high divorce rate, marriage at an all-time low, and aging population

Rebecca Wood,
Alzheimer's Research Trust

The study by the Karolinska Institute suggested that the problem might be even greater for some people.
Divorcees who remained single, they noticed, had a trebled risk of dementia, while those widowed at a young age who stayed single faced a six times greater chance.

The research looked at 1,449 people from a Finnish database, who were asked about their relationship status in mid-life, then revisited 21 years later to see if they had developed dementia.
In total, 139 of them had some sort of cognitive impairment, and Alzheimer's had been diagnosed in 48 of these.

Even after other factors which might have an impact on dementia were adjusted for, the study consistently showed people with partners as less prone to the illness.

Advice for the single

Dr Krister Hakansson, who led the study, said: "Living in a couple relationship is normally one of the most intense forms of social and intellectual stimulation.

"If social and cognitive challenges can protect against dementia, so should living as a couple.

Singletons shouldn't worry - there are many other ways to reduce your risk of dementia that don't involve popping the question

Susanne Sorenson,
Alzheimer's Society

"This study points to the beneficial effects of a married life."

Rebecca Wood, from the Alzheimer's Research Trust, said that more research along these lines was urgently needed.

"These findings are particularly worrying for the UK - a society with a high divorce rate, marriage at an all-time low, and aging population.

"This is the first study of its kind to examine the link between midlife marital status and dementia, adding to previous research suggesting that social interaction reduces dementia risk."

However, Susanne Sorenson, from the Alzheimer's Society, had some words of cheer for partnerless people.
She said: "Singletons shouldn't worry - there are many other ways to reduce your risk of dementia that don't involve popping the question.

"The best evidence is around eating a Mediterranean diet, exercising regularly and not smoking."

She also said that the findings were consistent with other research showing social interaction could be beneficial.

She added: "Whether it's reaching for the vacuum cleaner or going for long romantic walks, lifestyle factors associated with being married may also help."

Inactivity link to mental decline

Lack of exercise could lead to dementia in later life
Being a slob puts you at risk of mental health problems, experts have warned.
A lack of physical activity leads to depression and dementia, evidence presented at the British Nutrition Foundation conference shows.

It comes as new research from the University of Bristol found that being active cuts the risk of Alzheimer's disease by around a third.

Currently only 35% of men and 24% of women reach the recommended weekly amount of physical activity.

Professor Nanette Mutrie, an expert in exercise and sport psychology at the University of Strathclyde, told the conference that mental health was not a trivial issue.

It's only recently that people have begun to see the link between physical activity and mental health

Professor Nanette Mutrie

"It's only recently that people have begun to see the link between physical activity and mental health.

"It's important for increasing people's self esteem, general mood, coping with stress and even sleeping better.

"And we now have very strong evidence that physical activity can prevent depression."

She said inactive people had twice the risk of becoming depressed and there was also very good evidence that exercise is a useful treatment for depression.

Dementia risk

Researchers at the University of Bristol carried out an analysis of 17 trials looking at the effects of physical activity on dementia and Alzheimer's disease.

They found that in both men and women physical activity was associated with a 30-40% drop in the risk of Alzheimer's.

It is unclear why there is such a great effect but it could be associated with benefits to the vascular system as well as release of chemicals in the brain.

Professor Mutrie added: "It could be a simple case of use it or lose it.

"It is estimated that over 700,000 people in the UK currently suffer from dementia and more research is needed to determine how this condition can be prevented."

Professor Judy Buttriss, director general at the BNF, said with people living longer the implications of such studies were "enormous".

"There has already, justifiably, been a lot of emphasis on good nutrition but we must also find ways of helping people to be more physically active to ensure that they maintain health and quality of life in later years."

Department of Health figures show the majority of adults do not do the recommended 30 minutes of moderate activity at least five times a week.

Children are also leading increasingly inactive lives.

Around 30% of boys and almost 40% of girls fail to reach the recommended hour of moderate intensity activity per day.

Professor Chris Riddoch, expert in sport and exercise science at the University of Bath, said: "We have half a Century of evidence showing active people have lower levels of disease.

"We also have a very good handle on how much exercise people should take."
But he added efforts to get people to be more active had not been very successful to date.

Mary Joseph Foundation a non-profit organization for Alzheimer's disease

Diabetes and Head injury link to Alzheimer's disease

2009-09-18T07:44:00.000-07:00

People with either type 1 or type 2 diabetes face a greater risk of Alzheimer's disease and vascular cognitive impairment. Research indicates that this increase in risk may be due to a shared mechanism: a deficiency or dysfunction of insulin, the hormone that enables cells in the body to use blood sugar (glucose).

Brain cells need blood sugar in order to function, and in particular to execute a high-energy task such as learning a skill or forming a memory. Yet a 2005 study in the Journal of Alzheimer's Disease provides evidence that the brain's ability to use blood sugar may be compromised as Alzheimer's disease develops. The researchers found that insulin levels and the number of insulin receptors in the brain fall dramatically in the early stage of Alzheimer's disease, and they continue to plummet as the disease progresses. In the advanced stage of Alzheimer's disease, there are 80% fewer insulin receptors in the brain than is normal. The researchers think that the decline in insulin and insulin receptors in the brain may be linked somehow to the death of neurons and appearance of tangles in the brain — the signs of Alzheimer's disease.

Head injury

Many former boxers develop a condition called dementia pugilistica (boxer's dementia) after suffering repeated blows to the head. The microscopic changes in their brains resemble those in Alzheimer's disease, which led researchers to wonder if brain injury might be a factor in the disease. Researchers discovered amyloid deposits in people who died shortly after severe head injury, especially in those with the ApoE4 gene. The authors concluded that less severe head injuries might trigger amyloid deposits in susceptible people, resulting years later in full-blown Alzheimer's.

Mary Joseph Foundation a non-profit international organization for Alzheimer's disease

You Memory and Alzheimer's diaease.

2009-09-18T07:33:00.000-07:00

Autobiographical memory: Memory for the personal events and facts of one's life.

There is no single concept called " memory " There are two overarching types: short-term, which allows you to remember the beginning of this sentence by the time you reach the end of it, and long-term, which includes unconscious habits and reflexes, general facts and knowledge, and autobiographical memory ... memory for the personal details, facts and experiences of your life.

The brain has over 100 billion nerve cells (neurons). Each nerve cell communicates with many others to form networks.

Nerve cell networks have special jobs. Some are involved in thinking, learning and remembering. Others help us see, hear and smell. Still others tell our muscles when to move

Just like the rest of our bodies, our brains change as we age. Most of us notice some slowed thinking and occasional problems remembering certain things. However, serious memory loss, confusion and other major changes in the way our minds work are not a normal part of aging.

The term early-onset refers to Alzheimer's that occurs in a person under age 60. Early-onset individuals may be employed or have children still living at home. Issues facing families include ensuring financial security, obtaining benefits and helping children cope with the disease. People who have early-onset dementia may be in any stage of dementia – early, middle or late. Experts estimate that some 980,000 people in their 30s, 40s and 50s have Alzheimer's disease or a related dementia.

There are over 8 million Americans now have Alzheimer’s disease. Alzheimer's destroys brain cells, causing problems with memory, thinking and behavior severe enough to affect work, lifelong hobbies or social life. Alzheimer’s gets worse over time, and it is fatal. Today it is the seventh-leading cause of death in the United States.

Mary Joseph Foundation a non-profit international organization for Alzheimer' disease.

Mary Joseph Foundation

Alzheimer's disease and donations

2008-11-03T12:28:00.000-08:00

We cares

Our main gold is to eliminate Alzheimer's disease through the advancement of research; at the same time to provide and enhance care and support for all affected by this disease; and to reduce the risk of dementia through the promotion of brain health. We are working very hard so that one day there would be a world without Alzheimer's disease, but for now with your donations its allow us to build homes, give medicine, food and remove individuals who have Alzheimer's disease from the street who are homeless and from mental homes and cares for them.

There are still no CURE of any kind for Alzheimer's disease today on the world market... Dr.William Thomas.

'' Thank for your donations ''

Mary Joseph Foundation
137 1/2 Washington Ave, Suite 292
Belleville, NJ 07109

The deadly disease that effect us all.

2007-10-10T13:25:00.000-07:00

The long and slow goodbye.

Alzheimer’s disease was first diagnosed just over 100 years ago, yet it remains an area of high unmet medical need with a heavy burden of care. So where is research taking companies today?

Whoever and wherever the patient, Alzheimer’s disease can leave a trail of worn out, broken-hearted relatives as they care for their loved one on a journey that cannot be reversed.

Alzheimer’s is a progressive, irreversible brain disorder with a poorly understood cause and no known cure. It attacks and slowly steals the minds of its victim and brings heartache to the career, often a relative, who must watch their loved one slip away to a loathsome thief.

Symptoms of Alzheimer’s include memory loss, confusion, impaired judgment, personality changes, disorientation and loss of language skills. It is the most common form of irreversible dementia.

In the absence of better therapy, this global health problem will only get worse as populations age. It is estimated there will be over 61 million patients with dementia by 2020.

Understanding the needs of people with Alzheimer’s;

Our main gold is to eliminate Alzheimer's disease through the advancement of research; at the same time to provide and enhance care and support for all affected by this disease; and to reduce the risk of dementia through the promotion of brain health. We are working very hard so that one day there would be a world without Alzheimer's disease, but for now with your donations its allow us to build homes, give medicines, foods, vitamins, caring and remove individuals who have Alzheimer's disease from the street who are homeless and from mental homes and cares for them, our services are FREE.

In the case of Alzheimer’s, however, there is an additional need. “Alzheimer’s is a condition that affects not only the patient but also the career, the patient’s family and society as a whole."

While the core symptoms are memory and cognition loss, these can lead to other symptoms and physical ailments. "If an Alzheimer’s patient has trouble remembering the names of close friends and answering questions in social situations, chances are that this will eventually result in embarrassing social situations. In turn, this will lead to a lack of confidence and withdrawal,"
says Jason.

Alzheimer’s facts;

Today well over 30 million people worldwide are estimated to have Alzheimer’s
More than 50 per cent of people with Alzheimer’s live in developing countries. By 2050, this will be over 74 per cent
Alzheimer’s can occur at any age, even as young as 30 years in some rear cases.
The total worldwide cost by 2050 for Alzheimer's care is estimated to be well over US $460.4 billion annually.
It is currently not possible to predict who will get Alzheimer’s - it can strike anyone irrespective of gender, caste, creed, culture or socioeconomic status
21 September marks Alzheimer’s Disease Day, an umbrella body for Alzheimer’s groups around the world.

Brain changes precede memory loss;

In some cases the disease is very difficult to detect until it has progressed from mild memory loss to clear impairment, individuals eventually loss all ability to care for themselves.

The Brain structure changes can be seen in clinically normal individuals an average of two years before they are diagnosed with mild cognitive impairment.

In Dementia/Alzheimer's disease cases, lesions known as ( plaques and tangles ) form in the brain, due to the abnormal clumping of two proteins called beta-amyloid and tau.

MRI showed loss of gray matter two to three years before symptoms.

In normal older individuals, MRI of the brain reveals loss of gray matter about two to three years before symptoms of the mind cognitive impairment set in.

Dr. William Thomas

It hurt me very, very much that tears some times come to my eyes to see so much people here in America and around the world suffering from this deadly disease call Alzheimer's and the children who go with out foods and many are homeless.

Mary Joseph Foundation cares and we are doing everything possible to eliminate Alzheimer's disease, homelessness and hunger.

http://www.maryjosephfoundation.blogspot.com/

A God who listen to prayer.

2007-08-14T11:15:00.000-07:00

prayer:

O God Almighty, the God of my salvation, By day I have cried out, In the night ( also ) in front of you. Before you my prayer will come . Incline your ear to my entreating cry. For my soul has had enough of calamities, And my very life has come in touch even with She'ol.

My own eye has languished because of my affliction. I have called on you, O God Almighty, all day long; To you I have spread out my palms.

But you, O God Almighty, are a God merciful and gracious, Slow to anger and abundant in loving-kindness and trueness.