The deadly disease that effect us all.

The long and slow goodbye.

Alzheimer’s disease was first diagnosed just over 100 years ago, yet it remains an area of high unmet medical need with a heavy burden of care. So where is research taking companies today?

Whoever and wherever the patient, Alzheimer’s disease can leave a trail of worn out, broken-hearted relatives as they care for their loved one on a journey that cannot be reversed.

Alzheimer’s is a progressive, irreversible brain disorder with a poorly understood cause and no known cure. It attacks and slowly steals the minds of its victim and brings heartache to the career, often a relative, who must watch their loved one slip away to a loathsome thief.

Symptoms of Alzheimer’s include memory loss, confusion, impaired judgment, personality changes, disorientation and loss of language skills. It is the most common form of irreversible dementia.

In the absence of better therapy, this global health problem will only get worse as populations age. It is estimated there will be over 61 million patients with dementia by 2020.

Understanding the needs of people with Alzheimer’s;

Our main gold is to eliminate Alzheimer's disease through the advancement of research; at the same time to provide and enhance care and support for all affected by this disease; and to reduce the risk of dementia through the promotion of brain health. We are working very hard so that one day there would be a world without Alzheimer's disease, but for now with your donations its allow us to build homes, give medicines, foods, vitamins, caring and remove individuals who have Alzheimer's disease from the street who are homeless and from mental homes and cares for them, our services are FREE.

In the case of Alzheimer’s, however, there is an additional need. “Alzheimer’s is a condition that affects not only the patient but also the career, the patient’s family and society as a whole."

While the core symptoms are memory and cognition loss, these can lead to other symptoms and physical ailments. "If an Alzheimer’s patient has trouble remembering the names of close friends and answering questions in social situations, chances are that this will eventually result in embarrassing social situations. In turn, this will lead to a lack of confidence and withdrawal,"
says Jason.

Alzheimer’s facts;

• Today well over 30 million people worldwide are estimated to have Alzheimer’s
• More than 50 per cent of people with Alzheimer’s live in developing countries. By 2050, this will be over 74 per cent
• Alzheimer’s can occur at any age, even as young as 30 years in some rear cases.
• The total worldwide cost by 2050 for Alzheimer's care is estimated to be well over US $460.4 billion annually.
• It is currently not possible to predict who will get Alzheimer’s - it can strike anyone irrespective of gender, caste, creed, culture or socioeconomic status
• 21 September marks Alzheimer’s Disease Day, an umbrella body for Alzheimer’s groups around the world.

Brain changes precede memory loss;

In some cases the disease is very difficult to detect until it has progressed from mild memory loss to clear impairment, individuals eventually loss all ability to care for themselves.

The Brain structure changes can be seen in clinically normal individuals an average of two years before they are diagnosed with mild cognitive impairment.

In Dementia/Alzheimer's disease cases, lesions known as ( plaques and tangles ) form in the brain, due to the abnormal clumping of two proteins called beta-amyloid and tau.

MRI showed loss of gray matter two to three years before symptoms.

In normal older individuals, MRI of the brain reveals loss of gray matter about two to three years before symptoms of the mind cognitive impairment set in.

Dr. William Thomas

It hurt me very, very much that tears some times come to my eyes to see so much people here in America and around the world suffering from this deadly disease call Alzheimer's and the children who go with out foods and many are homeless.

Mary Joseph Foundation cares and we are doing everything possible to eliminate Alzheimer's disease, homelessness and hunger.

http://www.maryjosephfoundation.blogspot.com/